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Human Hemato-Lymphoid System Mice: Current Use and Future Potential for Medicine

To directly study complex human hemato-lymphoid system physiology and respective system-associated diseases in vivo, human-to-mouse xenotransplantation models for human blood and blood-forming cells and organs have been developed over the past three decades. We here review the fundamental requiremen...

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Detalhes bibliográficos
Main Authors: Rongvaux, Anthony, Takizawa, Hitoshi, Strowig, Till, Willinger, Tim, Eynon, Elizabeth E., Flavell, Richard A., Manz, Markus G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120191/
https://ncbi.nlm.nih.gov/pubmed/23330956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032712-095921
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