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Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
Mice with a functional human immune system have the potential to allow in vivo studies of human infectious diseases and to enable vaccine testing. To this end, mice need to fully support the development of human immune cells, allow infection with human pathogens, and be capable of mounting effective...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3038773/ https://ncbi.nlm.nih.gov/pubmed/21262803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019682108 |
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