Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

Mice with a functional human immune system have the potential to allow in vivo studies of human infectious diseases and to enable vaccine testing. To this end, mice need to fully support the development of human immune cells, allow infection with human pathogens, and be capable of mounting effective...

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Главные авторы: Willinger, Tim, Rongvaux, Anthony, Takizawa, Hitoshi, Yancopoulos, George D., Valenzuela, David M., Murphy, Andrew J., Auerbach, Wojtek, Eynon, Elizabeth E., Stevens, Sean, Manz, Markus G., Flavell, Richard A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038773/
https://ncbi.nlm.nih.gov/pubmed/21262803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019682108
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