Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

Hematopoietic stem cells (HSCs) both self-renew and give rise to all blood cells for the lifetime of an individual. Xenogeneic mouse models are broadly used to study human hematopoietic stem and progenitor cell biology in vivo. However, maintenance, differentiation, and function of human hematopoiet...

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Detalhes bibliográficos
Main Authors: Rongvaux, Anthony, Willinger, Tim, Takizawa, Hitoshi, Rathinam, Chozhavendan, Auerbach, Wojtek, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Eynon, Elizabeth E., Stevens, Sean, Manz, Markus G., Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038726/
https://ncbi.nlm.nih.gov/pubmed/21262827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019524108
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