Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

Hematopoietic stem cells (HSCs) both self-renew and give rise to all blood cells for the lifetime of an individual. Xenogeneic mouse models are broadly used to study human hematopoietic stem and progenitor cell biology in vivo. However, maintenance, differentiation, and function of human hematopoiet...

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Hauptverfasser: Rongvaux, Anthony, Willinger, Tim, Takizawa, Hitoshi, Rathinam, Chozhavendan, Auerbach, Wojtek, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Eynon, Elizabeth E., Stevens, Sean, Manz, Markus G., Flavell, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038726/
https://ncbi.nlm.nih.gov/pubmed/21262827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019524108
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