Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

Hematopoietic stem cells (HSCs) both self-renew and give rise to all blood cells for the lifetime of an individual. Xenogeneic mouse models are broadly used to study human hematopoietic stem and progenitor cell biology in vivo. However, maintenance, differentiation, and function of human hematopoiet...

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Main Authors: Rongvaux, Anthony, Willinger, Tim, Takizawa, Hitoshi, Rathinam, Chozhavendan, Auerbach, Wojtek, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Eynon, Elizabeth E., Stevens, Sean, Manz, Markus G., Flavell, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038726/
https://ncbi.nlm.nih.gov/pubmed/21262827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019524108
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