Peripheral blood CD34(+) cells efficiently engraft human cytokine knock-in mice

Human CD34(+) hematopoietic stem and progenitor cells (HSPCs) can reconstitute a human hemato-lymphoid system when transplanted into immunocompromised mice. Although fetal liver-derived and cord blood–derived CD34(+) cells lead to high engraftment levels, engraftment of mobilized, adult donor-derive...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Saito, Yasuyuki, Ellegast, Jana M., Rafiei, Anahita, Song, Yuanbin, Kull, Daniel, Heikenwalder, Mathias, Rongvaux, Anthony, Halene, Stephanie, Flavell, Richard A., Manz, Markus G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054696/
https://ncbi.nlm.nih.gov/pubmed/27543436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-676452
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