inv(16) and NPM1(mut) AMLs engraft human cytokine knock-in mice

Favorable-risk human acute myeloid leukemia (AML) engrafts poorly in currently used immunodeficient mice, possibly because of insufficient environmental support of these leukemic entities. To address this limitation, we here transplanted primary human AML with isolated nucleophosmin (NPM1) mutation...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Ellegast, Jana M., Rauch, Philipp J., Kovtonyuk, Larisa V., Müller, Rouven, Wagner, Ulrich, Saito, Yasuyuki, Wildner-Verhey van Wijk, Nicole, Fritz, Christine, Rafiei, Anahita, Lysenko, Veronika, Dudkiewicz, Ewa, Theocharides, Alexandre P., Soldini, Davide, Goede, Jeroen S., Flavell, Richard A., Manz, Markus G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084606/
https://ncbi.nlm.nih.gov/pubmed/27581357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-689356
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