A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft Versus Host Disease in Mouse Models()

Upon interaction with B7 homolog 1, Programmed Death-1 transmits a critical co-inhibitory signal to T cells to negatively regulate immune responses. By extensively searching the genomic database with the immunoglobulin variable region of PD-1, we identified a homolog and named it Programmed Death-1...

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Hlavní autoři: Flies, Dallas B, Wang, Shengdian, Xu, Haiying, Chen, Lieping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150865/
https://ncbi.nlm.nih.gov/pubmed/21768399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100660
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