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A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft Versus Host Disease in Mouse Models()
Upon interaction with B7 homolog 1, Programmed Death-1 transmits a critical co-inhibitory signal to T cells to negatively regulate immune responses. By extensively searching the genomic database with the immunoglobulin variable region of PD-1, we identified a homolog and named it Programmed Death-1...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150865/ https://ncbi.nlm.nih.gov/pubmed/21768399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100660 |
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