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Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability
Programmed death one homolog (PD-1H) is an immunoglobulin superfamily molecule and primarily acts as a coinhibitor in the initiation of T cell response to antigens. Here, we report that genetic ablation of PD-1H in mice blocks the differentiation of naive T cells to Foxp3(+) inducible Treg cells (iT...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5519767/ https://ncbi.nlm.nih.gov/pubmed/28729608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06410-w |
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