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Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

Mitotic homologous recombination promotes genome stability through the precise repair of DNA double-strand breaks and other lesions that are encountered during normal cellular metabolism and from exogenous insults. As a result, homologous recombination repair is essential during proliferative stages...

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Bibliografiske detaljer
Main Authors: Moynahan, Mary Ellen, Jasin, Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261768/
https://ncbi.nlm.nih.gov/pubmed/20177395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2851
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