Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease

Decoy lymphotoxin β receptor (LTβR) has potent immune inhibitory activities and thus represents a promising biologic for the treatment of inflammation, autoimmune diseases, and graft-versus-host disease (GVHD). As this reagent interrupts multiple molecular interactions, including LTβ-LTβR and LIGHT-...

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Detalhes bibliográficos
Main Authors: Xu, Yanhui, Flies, Andrew S., Flies, Dallas B., Zhu, Gefeng, Anand, Sudarshan, Flies, Sarah J., Xu, Haiying, Anders, Robert A., Hancock, Wayne W., Chen, Lieping, Tamada, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874563/
https://ncbi.nlm.nih.gov/pubmed/17179227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-047332
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