Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis

LIGHT is an important costimulatory molecule for T cell immunity. Recent studies have further implicated its role in innate immunity and inflammatory diseases, but its cellular and molecular mechanisms remain elusive. We report here that LIGHT is upregulated and functions as a proinflammatory cytoki...

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Opis bibliograficzny
Główni autorzy: Anand, Sudarshan, Wang, Pu, Yoshimura, Kiyoshi, Choi, In-Hak, Hilliard, Anja, Chen, Youhai H., Wang, Chyung-Ru, Schulick, Richard, Flies, Andrew S., Flies, Dallas B., Zhu, Gefeng, Xu, Yanhui, Pardoll, Drew M., Chen, Lieping, Tamada, Koji
Format: Artigo
Język:Inglês
Wydane: American Society for Clinical Investigation 2006
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409742/
https://ncbi.nlm.nih.gov/pubmed/16557300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27083
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