PD-1 on dendritic cells impedes innate immunity against bacterial infection

Programmed death one (PD-1) is an inducible molecule belonging to the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes and plays pivotal roles in the negative regulation of adaptive immune responses. We report here an unexpected finding: that PD-1 could also be induced on...

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Hlavní autoři: Yao, Sheng, Wang, Shengdian, Zhu, Yuwen, Luo, Liqun, Zhu, Gefeng, Flies, Sarah, Xu, Haiying, Ruff, William, Broadwater, Megan, Choi, In-Hak, Tamada, Koji, Chen, Lieping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700320/
https://ncbi.nlm.nih.gov/pubmed/19339692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-203141
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