Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM

The central nervous system (CNS) is an immune-privileged organ with the capacity to prevent excessive inflammation. Aside from the blood-brain barrier, active immunosuppressive mechanisms remain largely unknown. We report that a neuron-specific molecule, synaptic adhesion-like molecule 5 (SALM5), is...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhu, Yuwen, Yao, Sheng, Augustine, Mathew M., Xu, Haiying, Wang, Jun, Sun, Jingwei, Broadwater, Megan, Ruff, William, Luo, Liqun, Zhu, Gefeng, Tamada, Koji, Chen, Lieping
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846428/
https://ncbi.nlm.nih.gov/pubmed/27152329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500637
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