Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

Polycystic kidney disease (PKD) is an inherited disorder that is characterized by the accumulation of cysts in the renal parenchyma and progressive decline in renal function. Recent studies suggest that PKD arises from abnormalities of the primary cilium. We have previously shown that kidney-specifi...

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Main Authors: Patel, Vishal, Li, Ling, Cobo-Stark, Patricia, Shao, Xinli, Somlo, Stefan, Lin, Fangming, Igarashi, Peter
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150596/
https://ncbi.nlm.nih.gov/pubmed/18263895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn045
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