Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease

Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that establishes and maintains the structure of kid...

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Detalhes bibliográficos
Main Authors: Luyten, Annouck, Su, Xuefeng, Gondela, Sarah, Chen, Ying, Rompani, Santiago, Takakura, Ayumi, Zhou, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013531/
https://ncbi.nlm.nih.gov/pubmed/20705705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010127
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