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Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease

Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that establishes and maintains the structure of kid...

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Bibliografiset tiedot
Päätekijät: Luyten, Annouck, Su, Xuefeng, Gondela, Sarah, Chen, Ying, Rompani, Santiago, Takakura, Ayumi, Zhou, Jing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013531/
https://ncbi.nlm.nih.gov/pubmed/20705705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010127
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