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Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease
Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that establishes and maintains the structure of kid...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013531/ https://ncbi.nlm.nih.gov/pubmed/20705705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010127 |
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