Aberrant Regulation of Planar Cell Polarity in Polycystic Kidney Disease

Mutations in PKD1, which encodes polycystin-1 (PC1), contribute to >85% of cases of autosomal dominant polycystic kidney disease (ADPKD). The planar cell polarity (PCP) pathway is necessary for the oriented cell division and convergent extension that establishes and maintains the structure of kid...

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Bibliografiske detaljer
Main Authors: Luyten, Annouck, Su, Xuefeng, Gondela, Sarah, Chen, Ying, Rompani, Santiago, Takakura, Ayumi, Zhou, Jing
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2010
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013531/
https://ncbi.nlm.nih.gov/pubmed/20705705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010010127
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