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Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

Polycystic kidney disease (PKD) is an inherited disorder that is characterized by the accumulation of cysts in the renal parenchyma and progressive decline in renal function. Recent studies suggest that PKD arises from abnormalities of the primary cilium. We have previously shown that kidney-specifi...

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Hlavní autoři: Patel, Vishal, Li, Ling, Cobo-Stark, Patricia, Shao, Xinli, Somlo, Stefan, Lin, Fangming, Igarashi, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150596/
https://ncbi.nlm.nih.gov/pubmed/18263895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn045
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