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Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

Polycystic kidney disease (PKD) is an inherited disorder that is characterized by the accumulation of cysts in the renal parenchyma and progressive decline in renal function. Recent studies suggest that PKD arises from abnormalities of the primary cilium. We have previously shown that kidney-specifi...

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Detalhes bibliográficos
Main Authors: Patel, Vishal, Li, Ling, Cobo-Stark, Patricia, Shao, Xinli, Somlo, Stefan, Lin, Fangming, Igarashi, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150596/
https://ncbi.nlm.nih.gov/pubmed/18263895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn045
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