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ROLE OF THE Nrf2-ARE PATHWAY IN ACRYLAMIDE NEUROTOXICITY

Acrylamide (ACR) intoxication is associated with selective nerve terminal damage in the central and peripheral nervous systems. As a soft electrophile, ACR could form adducts with nucleophilic sulfhydryl groups on cysteine residues of kelch-like erythroid cell-derived protein with CNS homology-assoc...

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Detalhes bibliográficos
Main Authors: Zhang, Lihai, Gavin, Terrence, Barber, David S., LoPachin, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149808/
https://ncbi.nlm.nih.gov/pubmed/21540084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.04.011
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