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Joint Toxic Effects of the Type-2 Alkene Electrophiles

Human populations are exposed to complex environmental mixtures of acrolein, methylvinyl ketone (MVK) and other type-2 alkenes. Many members of this chemical class are electrophiles that possess a common molecular mechanism of toxicity; i.e., protein inactivation via formation of stable cysteine add...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Zhang, Lihai, Geohagen, Brian C., Gavin, Terrence, LoPachin, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936184/
https://ncbi.nlm.nih.gov/pubmed/27288850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.06.014
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