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Synaptosomal Toxicity and Nucleophilic Targets of 4-Hydroxy-2-Nonenal
4-Hydroxy-2-nonenal (HNE) is an aldehyde by-product of lipid peroxidation that is presumed to play a primary role in certain neuropathogenic states (e.g., Alzheimer disease, spinal cord trauma). Although the molecular mechanism of neurotoxicity is unknown, proteomic analyses (e.g., tandem mass spect...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638640/ https://ncbi.nlm.nih.gov/pubmed/18996889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn226 |
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