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Protective Properties of 2-Acetylcyclopentanone in a Mouse Model of Acetaminophen Hepatotoxicity

Our previous research showed that enolates formed from 1,3-dicarbonyl compounds, such as 2-acetylcyclopentanone (2-ACP), could provide protection in cell culture models from electrophile- or oxidative stress-induced toxicity. In the present study, we evaluated the protective abilities of 2-ACP in a...

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Autors principals: Zhang, Lihai, Gavin, Terrence, Geohagen, Brian C., Liu, Qiang, Downey, Katherine J., LoPachin, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716311/
https://ncbi.nlm.nih.gov/pubmed/23759509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.205435
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