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β-DICARBONYL ENOLATES: A NEW CLASS OF NEUROPROTECTANTS

Curcumin, phloretin and structurally related phytopolyphenols have well-described neuroprotective properties that appear to be at least partially mediated by 1,3-dicarbonyl enol substructures that form nucleophilic enolates. Based on their structural similarities, we tested the hypothesis that enola...

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Bibliografiske detaljer
Main Authors: LoPachin, Richard M., Gavin, Terrence, Geohagen, Brian C., Zhang, Lihai, Casper, Diana, Lekhraj, Rukmani, Barber, David S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998570/
https://ncbi.nlm.nih.gov/pubmed/21054388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.07091.x
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