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Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry

Background: Acrylamide (ACR) produces cumulative neurotoxicity in exposed humans and laboratory animals through a direct inhibitory effect on presynaptic function. Objectives: In this review, we delineate how knowledge of chemistry provided an unprecedented understanding of the ACR neurotoxic mechan...

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Main Authors: LoPachin, Richard M., Gavin, Terrence
Formato: Artigo
Idioma:Inglês
Publicado: National Institute of Environmental Health Sciences 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548275/
https://ncbi.nlm.nih.gov/pubmed/23060388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205432
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