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Common Molecular Determinants of Tarantula Huwentoxin-IV Inhibition of Na(+) Channel Voltage Sensors in Domains II and IV
The voltage sensors of domains II and IV of sodium channels are important determinants of activation and inactivation, respectively. Animal toxins that alter electrophysiological excitability of muscles and neurons often modify sodium channel activation by selectively interacting with domain II and...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149324/ https://ncbi.nlm.nih.gov/pubmed/21659528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246876 |
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