Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

The tumor suppressor p53 has been implicated in the pathogenesis of non-cancer-related conditions such as insulin resistance, cardiac failure, and early aging. In addition, accumulation of p53 has been observed in the hepatocytes of individuals with fibrotic liver diseases, but the significance of t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kodama, Takahiro, Takehara, Tetsuo, Hikita, Hayato, Shimizu, Satoshi, Shigekawa, Minoru, Tsunematsu, Hinako, Li, Wei, Miyagi, Takuya, Hosui, Atsushi, Tatsumi, Tomohide, Ishida, Hisashi, Kanto, Tatsuya, Hiramatsu, Naoki, Kubota, Satoshi, Takigawa, Masaharu, Tomimaru, Yoshito, Tomokuni, Akira, Nagano, Hiroaki, Doki, Yuichiro, Mori, Masaki, Hayashi, Norio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148730/
https://ncbi.nlm.nih.gov/pubmed/21747166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44957
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