The Bcl-2 Homology Domain 3 (BH3)-only Proteins Bim and Bid Are Functionally Active and Restrained by Anti-apoptotic Bcl-2 Family Proteins in Healthy Liver

An intrinsic pathway of apoptosis is regulated by the B-cell lymphoma-2 (Bcl-2) family proteins. We previously reported that a fine rheostatic balance between the anti- and pro-apoptotic multidomain Bcl-2 family proteins controls hepatocyte apoptosis in the healthy liver. The Bcl-2 homology domain 3...

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Detalhes bibliográficos
Main Authors: Kodama, Takahiro, Hikita, Hayato, Kawaguchi, Tsukasa, Saito, Yoshinobu, Tanaka, Satoshi, Shigekawa, Minoru, Shimizu, Satoshi, Li, Wei, Miyagi, Takuya, Kanto, Tatsuya, Hiramatsu, Naoki, Tatsumi, Tomohide, Takehara, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798470/
https://ncbi.nlm.nih.gov/pubmed/23986435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443093
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