Increased Bcl-xL Expression in Pancreatic Neoplasia Promotes Carcinogenesis by Inhibiting Senescence and Apoptosis

BACKGROUND & AIMS: Bcl-xL, an anti-apoptotic Bcl-2 family protein, is overexpressed in 90% of pancreatic ductal adenocarcinoma (PDAC) cases. However, Bcl-xL expression in pancreatic intraepithelial neoplasias (PanINs) and its significance in PDAC carcinogenesis remain unclear. The aim of this st...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Ikezawa, Kenji, Hikita, Hayato, Shigekawa, Minoru, Iwahashi, Kiyoshi, Eguchi, Hidetoshi, Sakamori, Ryotaro, Tatsumi, Tomohide, Takehara, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604117/
https://ncbi.nlm.nih.gov/pubmed/28948203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.02.001
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados