BH3-Only Protein Bid Participates in the Bcl-2 Network in Healthy Liver Cells

Bcl-2 homology domain 3 (BH3)-only protein Bid is posttranslationally cleaved by caspase-8 into its truncated form (tBid) and couples with stress signals to the mitochondrial cell death pathway. However, the physiological relevance of Bid is not clearly understood. Hepatocyte-specific knockout (KO)...

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Main Authors: Hikita, Hayato, Takehara, Tetsuo, Kodama, Takahiro, Shimizu, Satoshi, Hosui, Atsushi, Miyagi, Takuya, Tatsumi, Tomohide, Ishida, Hisashi, Ohkawa, Kazuyoshi, Li, Wei, Kanto, Tatsuya, Hiramatsu, Naoki, Hennighausen, Lothar, Yin, Xiao-Ming, Hayashi, Norio
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560855/
https://ncbi.nlm.nih.gov/pubmed/19839062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23207
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