Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

The tumor suppressor p53 has been implicated in the pathogenesis of non-cancer-related conditions such as insulin resistance, cardiac failure, and early aging. In addition, accumulation of p53 has been observed in the hepatocytes of individuals with fibrotic liver diseases, but the significance of t...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kodama, Takahiro, Takehara, Tetsuo, Hikita, Hayato, Shimizu, Satoshi, Shigekawa, Minoru, Tsunematsu, Hinako, Li, Wei, Miyagi, Takuya, Hosui, Atsushi, Tatsumi, Tomohide, Ishida, Hisashi, Kanto, Tatsuya, Hiramatsu, Naoki, Kubota, Satoshi, Takigawa, Masaharu, Tomimaru, Yoshito, Tomokuni, Akira, Nagano, Hiroaki, Doki, Yuichiro, Mori, Masaki, Hayashi, Norio
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148730/
https://ncbi.nlm.nih.gov/pubmed/21747166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44957
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares