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Sitamaquine Overcomes ABC-Mediated Resistance to Miltefosine and Antimony in Leishmania
Although oral miltefosine represented an important therapeutic advance in the treatment of leishmaniasis, the appearance of resistance remains a serious threat. LMDR1/LABCB4, a P-glycoprotein-like transporter included in the Leishmania ABC (ATP-binding cassette) family, was the first molecule shown...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147638/ https://ncbi.nlm.nih.gov/pubmed/21646479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00065-11 |
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