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Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug

Miltefosine (hexadecylphosphocholine [HePC]) is the first drug approved for the oral treatment of visceral leishmaniasis. As part of a study on the mechanisms of action of this drug and on the rates of resistance to this drug, we have been working in vitro with an Leishmania donovani line that was p...

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Bibliografische gegevens
Hoofdauteurs: Pérez-Victoria, F. Javier, Castanys, Santiago, Gamarro, Francisco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166066/
https://ncbi.nlm.nih.gov/pubmed/12878496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2397-2403.2003
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