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Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug

Miltefosine (hexadecylphosphocholine [HePC]) is the first drug approved for the oral treatment of visceral leishmaniasis. As part of a study on the mechanisms of action of this drug and on the rates of resistance to this drug, we have been working in vitro with an Leishmania donovani line that was p...

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Hlavní autoři: Pérez-Victoria, F. Javier, Castanys, Santiago, Gamarro, Francisco
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166066/
https://ncbi.nlm.nih.gov/pubmed/12878496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2397-2403.2003
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