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Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug
Miltefosine (hexadecylphosphocholine [HePC]) is the first drug approved for the oral treatment of visceral leishmaniasis. As part of a study on the mechanisms of action of this drug and on the rates of resistance to this drug, we have been working in vitro with an Leishmania donovani line that was p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166066/ https://ncbi.nlm.nih.gov/pubmed/12878496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2397-2403.2003 |
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