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Leishmania donovani Resistance to Miltefosine Involves a Defective Inward Translocation of the Drug

Miltefosine (hexadecylphosphocholine [HePC]) is the first drug approved for the oral treatment of visceral leishmaniasis. As part of a study on the mechanisms of action of this drug and on the rates of resistance to this drug, we have been working in vitro with an Leishmania donovani line that was p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pérez-Victoria, F. Javier, Castanys, Santiago, Gamarro, Francisco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC166066/
https://ncbi.nlm.nih.gov/pubmed/12878496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.8.2397-2403.2003
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