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Low Plasma Membrane Expression of the Miltefosine Transport Complex Renders Leishmania braziliensis Refractory to the Drug

Miltefosine (hexadecylphosphocholine, MLF) is the first oral drug with recognized efficacy against both visceral and cutaneous leishmaniasis. However, some clinical studies have suggested that MLF shows significantly less efficiency against the cutaneous leishmaniasis caused by Leishmania braziliens...

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Bibliografiske detaljer
Main Authors: Sánchez-Cañete, María P., Carvalho, Luís, Pérez-Victoria, F. Javier, Gamarro, Francisco, Castanys, Santiago
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663093/
https://ncbi.nlm.nih.gov/pubmed/19188379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01694-08
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