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Low Plasma Membrane Expression of the Miltefosine Transport Complex Renders Leishmania braziliensis Refractory to the Drug

Miltefosine (hexadecylphosphocholine, MLF) is the first oral drug with recognized efficacy against both visceral and cutaneous leishmaniasis. However, some clinical studies have suggested that MLF shows significantly less efficiency against the cutaneous leishmaniasis caused by Leishmania braziliens...

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Main Authors: Sánchez-Cañete, María P., Carvalho, Luís, Pérez-Victoria, F. Javier, Gamarro, Francisco, Castanys, Santiago
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663093/
https://ncbi.nlm.nih.gov/pubmed/19188379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01694-08
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