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Low Plasma Membrane Expression of the Miltefosine Transport Complex Renders Leishmania braziliensis Refractory to the Drug

Miltefosine (hexadecylphosphocholine, MLF) is the first oral drug with recognized efficacy against both visceral and cutaneous leishmaniasis. However, some clinical studies have suggested that MLF shows significantly less efficiency against the cutaneous leishmaniasis caused by Leishmania braziliens...

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Bibliografiska uppgifter
Huvudupphovsmän: Sánchez-Cañete, María P., Carvalho, Luís, Pérez-Victoria, F. Javier, Gamarro, Francisco, Castanys, Santiago
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663093/
https://ncbi.nlm.nih.gov/pubmed/19188379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01694-08
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