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Increased Glycolytic ATP Synthesis Is Associated with Tafenoquine Resistance in Leishmania major
Tafenoquine (TFQ), an 8-aminoquinoline used to treat and prevent Plasmodium infections, could represent an alternative therapy for leishmaniasis. Indeed, TFQ has shown significant leishmanicidal activity both in vitro and in vivo, where it targets Leishmania mitochondria and activates a final apopto...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067095/ https://ncbi.nlm.nih.gov/pubmed/21199921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-10 |
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