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Increased Glycolytic ATP Synthesis Is Associated with Tafenoquine Resistance in Leishmania major
Tafenoquine (TFQ), an 8-aminoquinoline used to treat and prevent Plasmodium infections, could represent an alternative therapy for leishmaniasis. Indeed, TFQ has shown significant leishmanicidal activity both in vitro and in vivo, where it targets Leishmania mitochondria and activates a final apopto...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067095/ https://ncbi.nlm.nih.gov/pubmed/21199921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-10 |
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