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Increased Glycolytic ATP Synthesis Is Associated with Tafenoquine Resistance in Leishmania major
Tafenoquine (TFQ), an 8-aminoquinoline used to treat and prevent Plasmodium infections, could represent an alternative therapy for leishmaniasis. Indeed, TFQ has shown significant leishmanicidal activity both in vitro and in vivo, where it targets Leishmania mitochondria and activates a final apopto...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067095/ https://ncbi.nlm.nih.gov/pubmed/21199921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-10 |
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