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A New ABC Half-Transporter in Leishmania major Is Involved in Resistance to Antimony
The characterization of ABCI4, a new intracellular ATP-binding cassette (ABC) half-transporter in Leishmania major, is described. We show that ABCI4 is involved in heavy metal export, thereby conferring resistance to Pentostam, to Sb(III), and to As(III) and Cd(II). Parasites overexpressing ABCI4 sh...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719772/ https://ncbi.nlm.nih.gov/pubmed/23716044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00211-13 |
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