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Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4(Cdt2) Ubiquitin Ligase Complex

CRL4(Cdt2) is a cullin-based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates implicated in the control of cell cycle and various DNA metabolic processes such as DNA replication and repair. Substrates for CRL4(Cdt2) E3 ubiquitin ligase include the replicati...

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Hlavní autoři: Shibata, Etsuko, Abbas, Tarek, Huang, Xinhua, Wohlschlegel, James A., Dutta, Anindya
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147600/
https://ncbi.nlm.nih.gov/pubmed/21628527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05496-11
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