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Identification of epigenetic DNA modifications with a protein nanopore
Two DNA bases, 5-methyl cytosine (5mC) and 5-hydroxymethylcytosine (hmC), marks of epigenetic modification, are recognized in immobilized DNA strands and distinguished from G, A, T and C by nanopore current recording. Therefore, if further aspects of nanopore sequencing can be addressed, the approac...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147113/ https://ncbi.nlm.nih.gov/pubmed/20927439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02864a |
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