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DNA STRETCHING AND OPTIMISATION OF NUCLEOBASE RECOGNITION FOR ENZYMATIC NANOPORE SEQUENCING

In nanopore sequencing, where single DNA strands are electrophoretically translocated through a nanopore and the resulting ionic signal is used to identify the four DNA bases, an enzyme has been used to ratchet the nucleic acid stepwise through the pore at a controlled speed. In this work, we invest...

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Detalhes bibliográficos
Publicado no:Nanotechnology
Main Authors: Stoddart, David, Franceschini, Lorenzo, Heron, Andrew, Bayley, Hagan, Maglia, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410315/
https://ncbi.nlm.nih.gov/pubmed/25648138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0957-4484/26/8/084002
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