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Nucleobase recognition in ssDNA at the central constriction of the αhemolysin pore

Nanopores are under investigation for single-molecule DNA sequencing. The α-hemolysin (αHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis of resid...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Stoddart, David, Heron, Andrew J., Klingelhoefer, Jochen, Mikhailova, Ellina, Maglia, Giovanni, Bayley, Hagan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935931/
https://ncbi.nlm.nih.gov/pubmed/20704324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl101955a
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