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Enhanced translocation of single DNA molecules through α-hemolysin nanopores by manipulation of internal charge
Both protein and solid-state nanopores are under intense investigation for the analysis of nucleic acids. A crucial advantage of protein nanopores is that site-directed mutagenesis permits precise tuning of their properties. Here, by augmenting the internal positive charge within the α-hemolysin por...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604925/ https://ncbi.nlm.nih.gov/pubmed/19060213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808296105 |
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