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Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes

Protein nanopores may provide a cheap and fast technology to sequence individual DNA molecules. However, the electrophoretic translocation of ssDNA molecules through protein nanopores has been too rapid for base identification. Here, we show that the translocation of DNA molecules through the α-hemo...

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Bibliografiske detaljer
Main Authors: Rincon-Restrepo, Marcela, Mikhailova, Ellina, Bayley, Hagan, Maglia, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391008/
https://ncbi.nlm.nih.gov/pubmed/21222450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1038874
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