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Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes

Protein nanopores may provide a cheap and fast technology to sequence individual DNA molecules. However, the electrophoretic translocation of ssDNA molecules through protein nanopores has been too rapid for base identification. Here, we show that the translocation of DNA molecules through the α-hemo...

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Autors principals: Rincon-Restrepo, Marcela, Mikhailova, Ellina, Bayley, Hagan, Maglia, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391008/
https://ncbi.nlm.nih.gov/pubmed/21222450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1038874
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