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Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes

Protein nanopores may provide a cheap and fast technology to sequence individual DNA molecules. However, the electrophoretic translocation of ssDNA molecules through protein nanopores has been too rapid for base identification. Here, we show that the translocation of DNA molecules through the α-hemo...

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Detalles Bibliográficos
Main Authors: Rincon-Restrepo, Marcela, Mikhailova, Ellina, Bayley, Hagan, Maglia, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391008/
https://ncbi.nlm.nih.gov/pubmed/21222450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1038874
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