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Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes

Protein nanopores may provide a cheap and fast technology to sequence individual DNA molecules. However, the electrophoretic translocation of ssDNA molecules through protein nanopores has been too rapid for base identification. Here, we show that the translocation of DNA molecules through the α-hemo...

詳細記述

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書誌詳細
主要な著者: Rincon-Restrepo, Marcela, Mikhailova, Ellina, Bayley, Hagan, Maglia, Giovanni
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391008/
https://ncbi.nlm.nih.gov/pubmed/21222450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1038874
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