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Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore

The sequencing of individual DNA strands with nanopores is under investigation as a rapid, low-cost platform in which bases are identified in order as the DNA strand is transported through a pore under an electrical potential. Although the preparation of solid-state nanopores is improving, biologica...

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Detalhes bibliográficos
Main Authors: Stoddart, David, Heron, Andrew J., Mikhailova, Ellina, Maglia, Giovanni, Bayley, Hagan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683137/
https://ncbi.nlm.nih.gov/pubmed/19380741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901054106
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