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Nucleobase recognition in ssDNA at the central constriction of the αhemolysin pore
Nanopores are under investigation for single-molecule DNA sequencing. The α-hemolysin (αHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis of resid...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2935931/ https://ncbi.nlm.nih.gov/pubmed/20704324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl101955a |
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