Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

Inhibitors of the serotonin transporter (SERT) and norepinephrine transporter (NET) are widely used in the treatment of major depressive disorder. Although SERT/NET selectivity is a key determinant for the therapeutic properties of these drugs, the molecular determinants defining SERT/NET selectivit...

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Hauptverfasser: Andersen, Jacob, Stuhr-Hansen, Nicolai, Zachariassen, Linda, Toubro, Søren, Hansen, Stinna M. R., Eildal, Jonas N. N., Bond, Andrew D., Bøgesø, Klaus P., Bang-Andersen, Benny, Kristensen, Anders S., Strømgaard, Kristian
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141962/
https://ncbi.nlm.nih.gov/pubmed/21730142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103060108
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