Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

Inhibitors of the serotonin transporter (SERT) and norepinephrine transporter (NET) are widely used in the treatment of major depressive disorder. Although SERT/NET selectivity is a key determinant for the therapeutic properties of these drugs, the molecular determinants defining SERT/NET selectivit...

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Bibliographic Details
Main Authors: Andersen, Jacob, Stuhr-Hansen, Nicolai, Zachariassen, Linda, Toubro, Søren, Hansen, Stinna M. R., Eildal, Jonas N. N., Bond, Andrew D., Bøgesø, Klaus P., Bang-Andersen, Benny, Kristensen, Anders S., Strømgaard, Kristian
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141962/
https://ncbi.nlm.nih.gov/pubmed/21730142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103060108
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