Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

Inhibitors of the serotonin transporter (SERT) and norepinephrine transporter (NET) are widely used in the treatment of major depressive disorder. Although SERT/NET selectivity is a key determinant for the therapeutic properties of these drugs, the molecular determinants defining SERT/NET selectivit...

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Detalhes bibliográficos
Main Authors: Andersen, Jacob, Stuhr-Hansen, Nicolai, Zachariassen, Linda, Toubro, Søren, Hansen, Stinna M. R., Eildal, Jonas N. N., Bond, Andrew D., Bøgesø, Klaus P., Bang-Andersen, Benny, Kristensen, Anders S., Strømgaard, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141962/
https://ncbi.nlm.nih.gov/pubmed/21730142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103060108
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